Mimix & Mimix QS Brochure Mimix & Mimix QS (German) Mimix & Mimix QS (Spanish)

Biomet Microfixation Mimix® and Mimix® QS Bone Replacement Systems.

Mimix® and Mimix® QS Bone Replacement System.
Mimix® and Mimix® QS are hydroxyapatite (HA) based mixtures of tetracalcium and an alpha (a)-tricalcium phosphate material ideal for the repair of cranial defects. Both share the same proven quality, but Mimix QS sets in less time, providing the surgeon with quicker closure.

The optimal handling properties of both Mimix and Mimix QS include fast, easy mixing and implantation in a moist field. The indications for both are for the repair of neurosurgical burr holes, craniotomy cuts and restoration and augmentation of bony contour in the craniofacial skeleton. All Mimix material is easily moldable, biocompatible and designed to maintain consistent volume and size once the product has set.

In general, the longer working time of Mimix allows for better contouring of large defects (25cm² size) while the shorter setting time of Mimix QS allows for quicker closure.

Mimix and Mimix QS Features

• Exhibits excellent biocompatibility
• More radiopaque than natural cranial bone and will not undergo any change in volume or size
• Mixed in an open bowl and sets in a typical surgical environment
• Sets at an isothermal temperature that will not damage surrounding tissue
• Easily shaped and molded for augmentation of small cranial defects as well as for onlay applications
• Can be placed directly on the dura

Properties

• Rapid Mixing: 30-45 seconds
• Working Time: 2-4 minutes
• Setting Time: 3-3.5 minutes
• Hardening Time: 4-6 minutes at 37°C
• Compression Strength: 3289 psi at 37°C
• Pore Size: 211 microns

Mimix® Mixing Instructions
It is important to note that Mimix material should not be mixed with hands because
the working time can be reduced significantly. Also, for optimal use, the Mimix powder
should not be mixed with any liquids other than the dilute citric acid provided.
1. After opening the sterile packaging, take the vial of Mimix powder and pour it into the
disposable bowl.
2. Next, take the vial of dilute citric acid, which is appropriately sized for the powder it is
packaged with, and pour all the liquid into the same mixing bowl.
3. Using the mixing spatula, blend the powder and liquid together until they form a dough-like paste.
4. When the correct consistency has been achieved, begin applying Mimix material from the
mixing bowl directly onto the defect site.

Mimix®QS Mixing Instructions

1. Open the sterile blister pouch and remove the Mimix QS bottles. Control hemostasis at the surgical site.
2. Open the bottle tops and empty the contents into the mixing bowl, taking care not to spill any liquid or powder. Ensure that all contents of bottles have
   been extracted.
3. Rapidly mix materials together for 30 seconds. Wait another 30 seconds and then apply the Mimix QS material to the defect. Complete all contouring within the one-to-two minute working time.
4. Mimix QS is an HA material that must be allowed to cure. While the material is setting, it must not be disturbed, because it could crack if manipulated. Allow the material to completely set before closing and do not attempt to drill directly into the implant, as this may cause the implant to shatter.

Note: For quality purposes, no more than 10 grams of Mimix QS should be mixed together at one time, or handling properties could be significantly altered. It is important to note that the Mimix material should not be mixed with hands, as the working time can reduce significantly. Also, for optimal use, the Mimix powder should not be mixed with other liquids, only the provided citric acid.

Mimix Handling Instructions
Spatula Dip Test - After the Mimix material has been mixed, insert the spatula into the paste and retract. When the spatula end leaves an impression in the material without the material filling in, it is ready to be applied to the field. If the indentation fills in too quickly, or the material is too runny, continue mixing, then try the dip test again. If the material is too firm to indent with the spatula, you have mixed it beyond the working time and must start over.

Another alternative is to place the mixed Mimix material on the side of the bowl and tilt the bowl sideways. If the material slides easily down the side, it is too runny. If the material stays in place, it is the desired consistency.

• Repair of neurosurgical burr holes, craniotomy cuts and other cranial defects
  
• Restoration or augmentation of bony contour in the craniofacial skeleton